AmateroPRPntchito kwenikweni?
01. Zotsatira za jekeseni wa PRP pamaso
Khungu laumunthu limakalamba chifukwa cha kuwonongeka kwa zigawo za collagen ndi elastin pansi pa khungu.Kuwonongeka kumeneku kumawonekera mwa mawonekedwe a mizere yabwino, makwinya ndi ziphuphu pamphumi, m'makona a maso, pakati pa nsidze ndi kuzungulira pakamwa.Mukhozanso kuona creases pa mapewa.Izi zimachitika pamene structural umphumphu wa collagen ulusi ndi kukokoloka chifukwa cha mkati ndi kunja zinthu.Kuchuluka kwa zinthu zakukulira mu PRP kukonzanso kolajeni ndikuyambitsa ma fibroblasts, kutsitsimutsa khungu ndikubwezeretsa mawonekedwe ake aunyamata.
02. Pamaso ndi Pambuyo pa PRP Chithandizo cha Tsitsi
Pofuna kuyesa mphamvu ya PRP pakutayika tsitsi, madokotala adayesa kumeta tsitsi pagulu la odwala mwachisawawa.Amagwira tsitsi pafupifupi 50 mpaka 60 ndikulichotsa pamutu.Asanalandire chithandizo, odwala ambiri adataya pafupifupi tsitsi 10.Bwerezani kuyesa kukoka tsitsi pambuyo pa magawo anayi a PRP masabata a 6 mosiyana.Odwala adanenanso kuchepa kwakukulu kwa tsitsi lotayika ndi zingwe za 3 zokha zomwe zimapatukana ndi scalp.Kuonjezera apo, dokotala amalemba mbali ina ya scalp kuti ayesedwe.PRP isanayambe komanso itatha kuyesedwa inasonyeza za 71 tsitsi la tsitsi ndi zoposa 93 tsitsi m'deralo, motero.
03. Zotsatira za PRP Knee Knee
Madokotala amafufuza gulu la odwala osteoarthritis omwe amatsimikiziridwa ndi MRI.Wodwala aliyense adalandira jekeseni imodzi kapena ziwiri za PRP pansi pa patella.Madokotala amawunika mkhalidwe wawo pakadutsa milungu 6, miyezi itatu, ndi miyezi isanu ndi umodzi.Iwo adapeza kuti odwala amamva ululu wochepa kwambiri komanso kuyenda bwino pa nthawi ya 6-sabata mpaka miyezi ya 3.Kugwira ntchito kwa bondo kunakulanso kwambiri.Miyezi isanu ndi umodzi pambuyo pake, zotsatira zake zinali zabwino kwambiri kuposa opaleshoni isanayambe, ngakhale kuti ululu ndi zochitika sizinali bwino.
04. Ndemanga ya PRP yaZiphuphu Ziphuphundi Marks
mlandu wathu
PRP yothandizira khungu la acne
Tulukani!Ziphuphu njonda
Malingana ndi kuopsa kwa pimple ndi kuwonongeka komwe kunayambitsa pakhungu, ziphuphu za ziphuphu zimatha kukhala zamitundu yosiyanasiyana, monga bokosi la bokosi, ice pick, ndi galimoto yogudubuza.Kuyika PRP mpaka 1 mm pansi pa chilonda kungathandize kuthetsa zipsera za acne.Ngati kuli kofunikira, dokotala angagwiritse ntchito singano zabwino kuti athyole minofu yolimba ya chipsera ndi keloid pachilonda kuti athe kuyankha bwino kuchipatala.
Microneedling ndi njira ina yomwe imagwiritsidwa ntchito popereka seramu pakhungu.Zinthu zakukula mu seramu ya PRP zimakonza collagen wosanjikiza pansi pa khungu.Khungu limayamba kuoneka ngati kamvekedwe kofanana chifukwa chosanjikizachi chimatulutsa ma cell atsopano ndikudumpha pakadutsa masabata 4 mpaka 6.Chithandizo chotsatira nthawi zonse chingathandize kubwezeretsa khungu.
05. Ndemanga za Chithandizo cha PRP kwa Zovulala za Tendon
Ochita maseŵera nthawi zambiri amavutika ndi kuvulala kwa tendon, kuvulala kwa rotator, ndi misozi ya Achilles tendon (monga osewera tennis ndi othamanga).Kutupa kwa tendon ya patellar m'dera la bondo ndi kuvulala kwina kofala.Kuphatikiza pa ululu wosiyanasiyana, othamanga amakumana ndi kutupa, kuvutika kuyenda, ndi kumveka phokoso pamene akusuntha mgwirizano womwe wakhudzidwa.
Kuvulala kwamasewera Majekeseni a PRP omwe amaikidwa pa malo okhudzidwa angathandize kuchiza kuvulala kwatsopano komanso kosatha.Pambuyo pa sabata la kutupa kowonjezereka mwamsanga pambuyo pa jekeseni wa PRP, wodwalayo adawona kusintha kwapang'onopang'ono pa masabata a 5 otsatirawa.Pochiza minofu yowuma, seramu ya PRP imatha kuchiritsa machiritso.Zotsatira zake, ululu ndi kutupa zimachepetsedwa pamodzi ndi kuyenda bwino.
06. Majekeseni a PRP a kuvulala kwa ligament ndi minofu
Malingana ndi minofu yomwe amagwiritsa ntchito mobwerezabwereza pa masewera awo, akatswiri othamanga amatha kuona kuvulala kwa ligament, minofu, ndi minofu.Mabondo ndi ntchafu ndi sprains, komanso kupweteka kwa hamstrings, nthawi zambiri kumayambitsa kutupa ndi kuvutika kuyenda.Kulowetsa PRP mu minofu yomwe yakhudzidwa ingathandize kuchira msanga.Mwanjira imeneyi, othamanga amatha kufupikitsa nthawi yochira ndikubwereranso kumunda mwachangu.Madokotala omwe adachita PRP asanayambe komanso atatha kujambula adawonetsa machiritso akuluakulu.
07. Ndemanga za Majekeseni a PRP Kwa Kusabereka
Kafukufukuyu adachitidwa pa gulu la amayi azaka zopitilira 40. Zoyeserera zam'mbuyomu zowathandiza kuti atenge pakati powaika mluza wa IVF zidalephera chifukwa khosi la chiberekero silinali lokhuthala mokwanira.Matendawa amalepheretsa implant kuti isagwirizane ndi chiberekero ndipo imatha kuyambitsa padera.Mothandizidwa ndi kuphatikiza kwa jekeseni wa PRP ndi zowonjezera za mahomoni, madokotala amatha kulimbikitsa kukula kwa chiberekero cha chiberekero.
Kuchiza kwa PRP kumathandiza kukwaniritsa makulidwe oyenera a 7mm mpaka 8mm kotero kuti amayi athe kutenga mimba mpaka nthawi yake.Majekeseni a PRP a kusabereka angathandizenso kukonza mazira ndi chiberekero mwa atsikana, kuwalola kupanga ndi kumasula mazira athanzi.Madokotala anakolola mazirawo ndi kuwakonzekeretsa IVF implantation, zomwe zimapangitsa kuti mwana abadwe wathanzi.
08. PRPzozungulira zakudapatsogolo ndi pambuyo
Kukalamba, zinthu zachilengedwe, kusowa tulo ndi matenda zimatha kuthandizira kupanga mabwalo amdima ndi maso otupa.Odwala amathanso kuona khungu lotayirira pansi pa maso kapena zomwe zimawoneka ngati zamadzimadzi m'matumba amaso.Majekeseni a PRP amatha kuthandizira pazochitika zonsezi popanga mitsempha yatsopano yamagazi pakhungu lolimba.Mitsempha yamagaziyi imadyetsa malowa ndi mpweya watsopano ndi zakudya komanso kuchotsa madzi ochuluka, poizoni ndi zosafunika.
Izi zisanachitike komanso pambuyo pa zotsatira za PRP zikuwonetsa bwino kuti zofooka zapakhungu monga hyperpigmentation, makwinya ndi khungu losalala zonse zatha, ndikuwulula maso owala.PRP imabwezeretsanso zigawo za collagen ndi elastin pakhungu, kubwezeretsa kulimba kwake.
Pamaso ndi Pambuyo pa PRP
Izi zisanachitike komanso pambuyo pa zithunzi za jekeseni wa PRP zimasonyeza bwino kuti pamene chithandizo cha PRP chikuchitidwa ndi dokotala wodziwika bwino, chimakhala ndi mwayi wothandiza anthu omwe ali ndi matenda osiyanasiyana ndi zodzoladzola.Kuphatikiza pazimene zili pamwambazi, PRP imadziwika kuti imathandizira kuchiritsa mabala, kupanga mafupa ndi kuyika mano opambana mu chisamaliro cha mano komanso ngakhale opaleshoni yotsegula mtima.M'zaka zikubwerazi, chithandizo cha PRP chingakhalenso ndi malangizo ena azachipatala ogwiritsira ntchito plasma (PRP) mu mafupa a mafupa pofuna kulimbikitsa kukonza mafupa.
Kuthyoka ndi kubwezeretsanso kukhulupirika kapena kupitiriza kwa fupa.Kuthyoka komwe sikunachiritsidwe pambuyo pa miyezi 9 ndipo sikuwonetsa zizindikiro za kuchira mkati mwa miyezi itatu kumatchedwa nonunion.Pali zifukwa zambiri zochedwetsera mgwirizano wa kusweka kapena kusagwirizana, monga kupunduka kwa mafupa, matenda, kusowa kwa zakudya m'thupi, kusakhazikika bwino, ndi kuchepa kwa magazi pachitsa.
Pali zifukwa zambiri zowopsa za fractures ndi nthawi yayitali ya matenda, kuchedwa kwa mgwirizano kapena kusagwirizana, ndipo chithandizo ndizovuta.Kuchedwetsa mgwirizano kapena kusagwirizana kwa fractures kumabweretsa ululu, kutayika kwa ntchito, ndi kusokoneza maganizo, zomwe zimapangitsa kuti moyo ukhale wochepa, kulephera kugwira ntchito, komanso kuchepetsa ndalama kwa odwala.Dziwani zomwe zimayambitsa kuchedwetsa kuchira mwachangu, perekani chithandizo munthawi yake, ndikuchepetsa ndalama zachipatala.Kafukufuku wawonetsa kuti kusuta ndi matenda a shuga ndizomwe zimayambitsa kuchedwa kwa mgwirizano, komanso kugwiritsa ntchito mankhwala oletsa kutupa (NSAIDs) kungayambitsenso kuchedwa kwa mgwirizano.Kuonjezera apo, kuvulala kwa minofu yofewa ndi matenda a mitsempha kumayambitsa zovuta zowonongeka, kuonjezera chiopsezo cha kuchedwa kwa mgwirizano kapena kusagwirizana.
Kugwiritsiridwa ntchito kwa platelet rich plasma (PRP) kumathandizira kuchiza machiritso a fracture.PRP imachokera ku magazi athunthu a autologous, omwe amasinthidwa mu vitro kuti apange kukonzekera kokhala ndi mapulateleti, omwe ali ndi zinthu zosiyanasiyana za kukula zomwe zimapangidwira panthawi yokonza kuwonongeka kwa mafupa.Kafukufuku wasonyeza kuti PRP ili ndi zotsatira zolimbikitsa osteogenesis, zomwe zingathe kulimbikitsa machiritso ndi kukonzanso kwa fractures, mafupa a mafupa, nonunion, osteonecrosis, osteoporosis, kusokonezeka kwa msana, matenda a mafupa ndi kusokoneza osteogenesis.Malangizo azachipatala ndi chida chabwino kwambiri kwa asing'anga ndi odwala kuti apange zisankho zachipatala, ndi cholinga chomaliza cha matenda okhazikika, omveka komanso ogwira mtima komanso ochizira matenda.Ndi kafukufuku wochulukirachulukira komanso kugwiritsa ntchito PRP m'malo a mafupa, umboni watsopano wachipatala wokhudzana ndi umboni wachipatala wapangidwa m'zaka zaposachedwa.Pofuna kuyendetsa bwino ntchito ya PRP mu mafupa a mafupa, chitsogozo ichi chinapangidwa malinga ndi umboni wamakono.
kukonza fupa
Kuchiritsa fracture ndi kukonza minofu ya mafupa kumaphatikizapo magawo awiri:
Gawo loyamba ndi gawo loyamba la anabolic, lomwe limadziwika ndi kulembedwa ndi kusiyanitsa kwa maselo oyambira kuti apange mafupa ndi mitsempha yamagazi, komanso mapangidwe a cartilage.
Gawo lachiwiri ndi gawo la catabolic, lomwe limadziwika ndi resorption ya cartilage pomwe imagwiranso ntchito ngati template yopanga fupa latsopano m'malo mwa chichereŵechereŵe.Pambuyo pake, minofu ya callus imabwezeretsedwa ndipo fupa lomwe langopangidwa kumene limakonzedwanso kukhala cortical bone in situ.
Machiritso onse ndi zotsatira zachilengedwe za kuchuluka kwa maselo ogwirizana ndi chizindikiro mkati mwa minofu yosinthika.Kumayambiriro kwa kuvulala kwa fracture, minofu ya m'deralo imapanga zinthu zowonongeka, zomwe zimakhala ngati amithenga am'deralo ndi amtundu uliwonse panthawi ya machiritso a mafupa, ndipo zimakhala ndi zotsatira zolimbikitsa machiritso a fracture.Kusakhazikika kwa zinthu zachilengedwezi kungayambitse kuchira kwa mafupa.
PRP kukula factor
Kukonzanso kwa mafupa a platelet concentrate kumatha kukhala chifukwa cha kukula kwa osteogenic komwe kuli.Pambuyo pa mapulateleti omwe ali m'mapulateleti osakanikirana ndi calcium ndi / kapena prothrombin, mapulateleti a alpha granules amatulutsa zinthu zosiyanasiyana za kukula kudzera mu exocytosis, monga vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), kusintha kukula kwa factor- β. (TGF-β), insulin-like growth factor (IGF), epidermal growth factor (EGF), etc., zonsezi zimakhala ndi zotsatira za osteogenic.
vascular endothelial kukula factor
Ikhoza kuthandizira ndikugwirizanitsa mapangidwe oyambirira a mitsempha ya magazi ndi ziwalo zina poyendetsa kusamuka, kufalikira ndi kusiyanitsa kwa mitsempha ya mitsempha ya endothelial.Panthawi imodzimodziyo, ikhoza kulimbikitsa kusiyana kwa osteoblasts ndipo ndizofunikira kwambiri pakukula kwa fupa.
Kukula kwa mapulateleti opangidwa ndi maselo
Mapulateleti ophatikizidwa kuchokera kumalekezero othyoka amapangidwa mochuluka ndipo amawonekera mosalekeza panthawi yonse yochira.Amatha kuyendetsa kusamuka ndi kufalikira kwa maselo oyambira, ndikulimbikitsa kufalikira ndi kusiyanitsa kwa osteoblasts.
kusintha kukula factor-beta
Imatha kuyambitsa chemotaxis ndi mitosis ya fibroblasts ndi osteoblasts, kuwongolera kukula kwa maselo ndi kuchuluka kwa osteoblasts, kuyambitsa kaphatikizidwe ka matrix a mafupa, kukonzanso matrix a extracellular, ndikulimbikitsa machiritso a mafupa.Kuchepa kwa TGF-β kungagwirizane ndi kuchedwa kwa mafupa a mgwirizano kapena kusagwirizana.
kukula kwa hormone
(growth hormone, GH)/insulin-like growth factor-1 (IGF-1) imagwirizanitsidwa ndi kuchedwa kwa mgwirizano wa fupa kapena nonunion, ndipo amatenga nawo mbali pakukula kwa maselo a mesenchymal stem, maselo a periosteal, chondrocytes, osteoblasts, ndi osteoclasts ndi kusiyanitsa. , kuwongolera mapangidwe a mafupa, kulimbikitsa osteoblasts ndi chondrocytes kuti atulutse vascular endothelial growth factor, ndi kulimbikitsa angiogenesis.
Zotsatira zotsutsa-kutupa za PRP
Ma leukocyte m'mapulateleti okhazikika amapangitsa kuti nyukiliya factor kB (nuclear factor kappa B, NF-kB) iwonetsere kukulitsa kuyankha kwa kutupa pansi pakuchita kwa fibroblasts ndi osteoblasts.TNF-α, monga cytokine yaikulu ya kuyankha kotupa, ikhoza kulimbikitsa kutulutsidwa kwa TGF-β.TGF-β ili ndi immunostimulatory ntchito kumayambiriro kwa kutupa kapena pamtunda wochepa, ndipo imatha kusonkhanitsa maselo otupa;pamagulu akuluakulu, amatha kulepheretsa kukula ndi ntchito za maselo otupa monga T, B lymphocytes, ndi macrophages, ndikuletsa maselo a cytotoxic T.Tetezani thupi ku chitetezo chamthupi ndikuletsa kuyankha kotupa.
Anti-infective effect ya PRP
Anti-infective effect ya platelet concentrate imachokera ku mapulateleti ndi maselo oyera a magazi omwe ali nawo.Mapulateleti m'mapulateleti okhazikika amatulutsa ma peptide antibacterial, omwe amatha kuwononga ma cell a bakiteriya, amalepheretsa kaphatikizidwe ka RNA, kaphatikizidwe ka mapuloteni kapena mapuloteni, amalepheretsa poizoni wa bakiteriya, yambitsa dongosolo la autolysis la bakiteriya, kenako ndikuwonetsa zotsatira za antibacterial.Ma leukocyte amatha kukhala pakati pa chitetezo cham'manja, kuyambitsa ma neutrophils, ndikumeza tizilombo toyambitsa matenda kudzera m'ma cytokines osiyanasiyana ndi mapuloteni achilengedwe.Kafukufuku wasonyeza kuti anaikira mapulateleti okhala ndi chiwerengero chachikulu cha maselo oyera a magazi angathe kuchepetsa titer wa Staphylococcus aureus.Kuyesera kwa antibacterial mu vitro kunasonyeza kuti PPR inali ndi zotsatira za antibacterial pa Staphylococcus aureus, Escherichia coli, Streptococcus agalactiae, ndi Shigella, koma sizinakhudze Pseudomonas aeruginosa, Klebsiella pneumoniae, ndi Serratia.Magazi onse analibe antibacterial effect pa mabakiteriya omwe tawatchulawa.
Pomaliza
1. Kuphatikiza mapulateleti okhazikika kumatha kufulumizitsa kuchira kwa fracture ndikufupikitsa kukhala m'chipatala.
2. Ikhoza kufulumizitsa kuchiritsa kwa kusagwirizana ndi kufupikitsa chipatala.
3. Kwa odwala omwe ali ndi fractures, nonunnion, ndi mafupa opunduka, kugwiritsidwa ntchito kwa platelet concentrate sikudzawonjezera zochitika zowopsya, monga matenda, kufiira kwapafupi, ndi kutupa.
4. Kwa osasunthika komanso okhazikika atrophic nonunion, jekeseni wamba wa platelet concentrate angachepetse mwayi woyambiranso.
5. Mapulateleti okhazikika amatha kulimbikitsa kukonzanso kwa kusuta, kusweka kwa matenda a shuga, kusagwirizana, ndi kuwonongeka kwa mafupa.
6. Pochiza fractures, nonunnion, ndi zofooka za mafupa pamodzi ndi matenda, leukocyte-protelet concentrate ingakhale yabwino kusiyana ndi leukocyte-osauka ku platelet concentrate.
Takulandirani kuti mulumikizane ndi Amain technology Co,.;Ltd, kuti akupatseni ndondomeko yamankhwala ya PRP, reagent ya PRP + PRP yotolera magazi chubu.
Joy uwu
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Malingaliro a kampani Sichuan Amain Technology Co., Ltd.
Nthawi yotumiza: Mar-15-2023
