Faahfaahin Deg Deg ah
Cassette-ka Dengue Combo Test Cassette (Dhiigga oo Dhan/ Serum/ Plasma) waa immunoassay chromatographic degdeg ah oo loogu talagalay ogaanshaha tayada ee NS1 antigen iyo IgG iyo IgM unugyada difaaca jirka ee fayraska Dengue ee dhiigga oo dhan, serum, ama balaasmaha si ay gargaar ugu noqoto ogaanshaha Dengue caabuqa.
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Tilmaamaha
AMRDT001 Dengue Combo Cassette Tijaabo Degdeg ah
Cassette-ka Dengue Combo Test Cassette (Dhiigga oo Dhan/ Serum/ Plasma) waa immunoassay chromatographic degdeg ah oo loogu talagalay ogaanshaha tayada ee NS1 antigen iyo IgG iyo IgM unugyada difaaca jirka ee fayraska Dengue ee dhiigga oo dhan, serum, ama balaasmaha si ay gargaar ugu noqoto ogaanshaha Dengue caabuqa.
Dengue waa flavivirus, waxaa gudbiya kaneecada Aedes aegypti iyo Aedes albopictus.Waxa si weyn loogu qaybiyaa guud ahaan dhulka kulaala iyo kulaalayaasha hoose ee aduunka,1 waxana uu sababaa ilaa 100 milyan oo caabuq sanadkiiba.Caabuqa Dengue ee aasaasiga ah wuxuu keenaa unugyada difaaca IgM inay kordhiyaan heer la ogaan karo 3 ilaa 5 maalmood ka dib bilawga qandhada.Unugyada difaaca jirka ee IgM guud ahaan waxay ku sii jiraan 30 ilaa 90 maalmood.3 Bukaanjiifka Dengue intooda badan ee gobollada endemic waxay leeyihiin infekshannada labaad, 4 taasoo keentay heerar sare oo ah unugyada difaaca IgG ee gaarka ah ka hor ama isla mar ahaantaana jawaabta IgM.5 Sidaa darteed, ogaanshaha gaar ah anti-Dengue IgM iyo Unugyada difaaca jirka ee IgG waxay kaloo kaa caawin karaan inay kala soocaan caabuqyada asaasiga ah iyo kuwa sare.NS1 waa mid ka mid ah 7 Dengue Virus oo aan qaab dhismeed ahayn kuwaas oo loo malaynayo inay ku lug leeyihiin taranka fayraska.NS1 waxay u jirtaa monomer ahaan qaabkeeda aan qaan-gaarin laakiin si degdeg ah ayaa looga baaraandegaa xuubka endoplasmic si loo sameeyo dimer deggan.Qadar yar oo NS1 ah ayaa ku hadhaya oo la xidhiidha xubnaha intracellular halka loo malaynayo inay ku lug leeyihiin taranka fayraska.Inta soo hartay ee NS1 waxaa laga helaa iyadoo lala xiriirinayo xuubka balaasmaha ama waxaa loo siray sidii hexadimer milmaya.NS1 waxay lama huraan u tahay jiritaanka fayraska laakiin shaqadeeda bayooloji ee saxda ah lama garanayo.Unugyada difaaca jirka ee loo kiciyo jawaabta NS1 ee caabuqa fayrasku waxay ka gudbi karaan falcelinta antigens-ka unugyada unugyada unugyada epithelial iyo platelet, taasina waxay lug ku leedahay horumarinta qandhada Hemorrhagic Dengue.
AMRDT001 Dengue Combo Cassette Tijaabo Degdeg ah
Kaassette-ka Dengue IgG/IgM ee Tijaabada Degdegga ah (Dhiigga Dhan/Serum/ Plasma) waa tallaal tayo leh oo xuub-ku-saleysan oo lagu ogaanayo unugyada difaaca Dengue ee dhiigga oo dhan, serum, ama balaasmaha.Tijaabadani waxay ka kooban tahay laba qaybood, qayb IgG ah iyo qayb IgM ah.Qaybta IgG, ka-hortagga aadanaha IgG waxaa lagu dahaadhay gobolka khadka tijaabada IgG.Inta lagu jiro tijaabada, muunadu waxay ka falcelinaysaa walxaha Dengue antigen-ku dahaadhay ee cajaladda tijaabada ah.Isku darka ayaa markaa kor ugu guura xuubka chromatographically iyadoo la raacayo ficilka xididada waxayna la falgalaan ka-hortagga bini'aadamka IgG ee gobolka khadka tijaabada IgG.Haddii muunada ay ka kooban tahay unugyada difaaca IgG ee Dengue, xariiq midabaysan ayaa ka soo bixi doona gobolka khadka tijaabada IgG.Qaybta IgM, IgM-ka-hortagga bini'aadamka waxaa lagu dahaadhay gobolka khadka tijaabada IgM.Inta lagu jiro tijaabada, muunadu waxay ka falcelinaysaa IgM-ka-hortagga aadanaha.Unugyada difaaca Dengue IgM, haddii ay ku jiraan muunada, waxay la falgalaan ka-hortagga aadanaha IgM iyo walxaha Dengue antigen-dahaarka ah ee ku jira cajaladda tijaabada, dhismahan waxaa qabta IgM-ka-hortagga bini'aadamka, sameynta xariiq midab leh oo ku yaal gobolka khadka tijaabada IgM .Sidaa darteed, haddii muunada ay ka kooban tahay unugyada difaaca jirka ee Dengue IgG, xariiq midab leh ayaa ka soo bixi doona gobolka khadka tijaabada IgG.Haddii muunada ay ka kooban tahay unugyada difaaca Dengue IgM, xariiq midabaysan ayaa ka soo bixi doona gobolka khadka tijaabada IgM.Haddii muunada aysan ku jirin unugyada difaaca jirka ee Dengue, xarriiq midab leh kama soo bixi doono labada gobol ee xarriiqda tijaabada ah, taasoo muujineysa natiijo xun.Si loogu adeego hab-socodka xakamaynta, xariiq midabaysan ayaa had iyo jeer ka soo muuqan doona gobolka xariiqda kantaroolka, taas oo muujinaysa in mugga saxda ah ee muunada lagu daray iyo xuubka xuubka ayaa dhacay.
AMRDT001 Dengue Combo Cassette Tijaabo Degdeg ah
Kaassette-ka Dengue NS1 ee Tijaabada Degdegga ah (Dhiigga Dhan/Serum/Balaasmaha) waa tallaal tayo leh oo xuub-ku-saleysan oo lagu ogaado Dengue NS1 antigen ee dhiigga oo dhan, serum, ama balaasmaha.Inta lagu jiro tijaabada, muunadu waxay ka falcelinaysaa Dengue antibody-conjugate gudaha cajaladda tijaabada.Isku-xidhka ka-hortagga Dahabka wuxuu ku xidhi doonaa Dengue antigen muunadda muunada taasoo iyaduna ku xidhmi doonta Anti-Dengue NS1 oo lagu dahaadhay xuubka.Marka reagent-ku u gudbo guud ahaan xuubka, difaaca Dengue NS1 ee xuubka ayaa xidhi doona isku-dhafka antibody-antigen taasoo keenaysa khad midab casaan ah ama midab casaan ah inuu ka sameeyo gobolka xariiqda tijaabada ee xuubka tijaabada.Xoojinta xariiqdu way kala duwanaan doontaa iyadoo ku xidhan cadadka antigen-ka ku jira muunada.Muuqaalka xariiqa casaanka ah ee gobolka tijaabada waa in loo tixgeliyaa natiijo wanaagsan.【REAGENTS】 Cajalka tijaabada degdega ah ee Dengue IgG/IgM waxa uu ka kooban yahay Dengue antigen isku xidha dahab kolloid, anti-aadmiga IgM, anti-aadmiga IgG dahaarka leh xuubka.Cassette-ka Dengue NS1 Degdegga ah ee Tijaabada Dengue wuxuu ka kooban yahay walxaha kolloid-ka-hortagga-Dengue Ag, oo ka-hortagga Dengue Ag oo lagu dahaadhay xuubka.
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