Ikhithi Yokuhlola Esheshayo ye-Lepu Antigen AMRPA77

Ikhithi Yokuhlola Esheshayo ye-Lepu Antigen AMRPA77 Ehloselwe Ukusetshenziswa
Umkhiqizo uhloselwe ukutholwa kwekhwalithi ye-antigen ngokumelene ne-SARS-CoV-2 kumasampula omtholampilo (i-nasal swab).

Ikhithi Yokuhlola Esheshayo ye-Lepu Antigen AMRPA77

Ayihlaseleki
Kulula ukuyisebenzisa
Ilula, awekho amadivayisi adingekayo
Ngokushesha, thola umphumela emizuzwini eyi-15
Izinzile, ngokunemba okuphezulu
Okungabizi, ukonga imali

Isifinyezo Sekhithi Yokuhlola Esheshayo ye-Lepu Antigen ye-AMRPA77
ICoronavirus, njengomndeni omkhulu wegciwane, iyigciwane le-RNA elinemvilophu elilodwa elinemvilophu.Leli gciwane laziwa ngokudala izifo ezinkulu ezinjengomkhuhlane, Middle East Respiratory Syndrome (MERS), kanye neSevere Acute Respiratory Syndrome (SARS).

Iphrotheni ewumgogodla ye-SARS-CoV-2 yi-N protein (Nucleocapsid), okuyingxenye yamaprotheni etholakala ngaphakathi kwegciwane.Ilondolozwe ngokuqhathaniswa phakathi kwe-β-coronavirus futhi ivame ukusetshenziswa njengethuluzi lokuxilonga i-coronavirus.I-ACE2, njengesamukeli esibalulekile sokuthi i-SARS-CoV-2 ingene kumaseli, ibaluleke kakhulu ocwaningweni lwendlela yokutheleleka ngegciwane.

Ikhithi Yokuhlola Esheshayo ye-Lepu Antigen ye-AMRPA77
Ikhadi lokuhlola lamanje lisekelwe ekuphenduleni okuthile kwe-antibody-antigen kanye nobuchwepheshe be-immunoanalysis.Ikhadi lokuhlola liqukethe i-colloidal yegolide ebhalwe ukuthi SARS-CoV-2 N protein monoclonal antibody efakwe ngaphambili kuphedi yenhlanganisela, ehambisana ne-SARS-CoV-2 N protein monoclonal antibody engakwazi ukuhamba endaweni yokuhlola (T) kanye ne-antibody ehambisanayo ngekhwalithi. indawo yokulawula (C).

Ngesikhathi sokuhlolwa, iphrotheni engu-N kusampula ihlangana negolide eliqinile elibhalwe ukuthi SARS-CoV-2 N protein monoclonal antibody embozwe ngaphambili kuphedi yenhlanganisela.Ama-conjugate afuduka aye phezulu ngaphansi komphumela we-capillary, futhi ngemva kwalokho athathwe i-N protein monoclonal antibody enganyakazi endaweni yokuhlola (T).

Ukuphakama kokuqukethwe kwe-N protein kusampula, kulapho ama-conjugate athwebula khona futhi umbala endaweni yokuhlola uba mnyama.

Uma lingekho igciwane kusampula noma okuqukethwe kwegciwane kungaphansi komkhawulo wokutholwa, kusho ukuthi awukho umbala oboniswa endaweni yokuhlola (T).

Kungakhathalekile ukuba khona noma ukungabikho kwegciwane kusampula, kuzovela umugqa onsomi endaweni yokulawula ikhwalithi (C).

Umugqa onsomi endaweni yokulawula ikhwalithi (C) umbandela wokunquma ukuthi ikhona yini isampula eyanele noma cha nokuthi inqubo yechromatography ijwayelekile yini.